Product Description

Discover the best selection of siRNA for superior gene silencing using Thermo Scientific Dharmacon® pre-designed siRNA reagents. Achieve highly effective gene silencing from the RNAi experts using genome-wide siRNA available for human, mouse, and rat.

Dharmacon siRNA reagents are the most used and most trusted in the industry. siGENOME® siRNA reagents were recently updated to reflect the latest gene sequence information to make them even more reliable and potent than ever. ON-TARGETplus® siRNA reagents are bioinformatically optimized and chemically modified to reduce off-target effects up to 90% for more accurate results and decreased false positives. Both siGENOME and ON-TARGETplus product lines offer guaranteed silencing of 75% or better. Accell™ siRNA reagents are specially modified provide delivery into any cell type, without a transfection reagent, for unprecedented experimental flexibility and discovery.

Benefits

Accell siRNA

• Deliver into any cell type without a transfection reagent, for unprecedented flexibility and discovery
• Leave lengthy delivery optimization behind and enjoy extraordinary ease-of-use for rapid results
• Eliminate non-specific lipid effects to uncover your true phenotype

ON-TARGETplus siRNA

• The only dual-strand modification to address off-target effects caused by both the sense and antisense strand
• Proven reduction in off-targets of up to 90% for fewer false phenotypes
• Cutting-edge seed-region analysis improves siRNA specificity

siGENOME siRNA

• Superior SMARTselection™ designs provide highly potent specific silencing
• Re-versioned in 2008 to reflect the most current RefSeq data
• SMARTpool® technology provides higher specificity and the best single-reagent guarantee available

Dharmacon siRNA Control Reagents

• Validated RNAi controls to ensure experimental reproducibility
• Broad selection for multiple experimental applications
• Positive and negative controls available for Accell, ON-TARGETplus, and siGENOME siRNA reagents

Dharmacon siRNA Libraries

• Combine the unmatched format flexibility of siRNA pools and individuals with superior silencing for guaranteed results
• Over 50 siRNA libraries available for Accell, ON-TARGETplus, and siGENOME siRNA

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